The results of correlation coefficient indicated that there were significant ( P ≤ 0.05) positive correlations between TP and Glo for uterus and breast cancer patients and between TP and Alb for ovary cancer patients. showed significant ( P ≤ 0.05) decrease in all patients group except patients with breast cancer showed significant increase ( P ≤ 0.05) compared to healthy participants. Results: Alb levels significantly ( P ≤ 0.05) decreased in all patient samples except those with uterus cancer who showed significant increase ( P ≤ 0.05) compared to healthy participants, and Glo levels significantly ( P ≤ 0.05) decreased for uterus and breast cancer samples and nonsignificant ( P ≤ 0.05) decrease in patients with ovary cancer compared to healthy participants finally, the ratio of Alb./Glo. Materials and Methods: This study included 120 females with (28 uteri, 31 ovaries, and 25 breasts) cancer patients and 36 healthy control participants, with age ranges between (20 and 42) years. Objective: This study aimed to investigate the levels of the total protein (TP), albumin (Alb), globulin (Glo), and Alb/Glo ratio in the female patients with (uterus, ovary, and breast) cancer compared to healthy females. Background: Gynecological cancer is one of the most serious public health problems in the world with main gynecological cancers, uterus, breast, and ovarian, causing morbidity with severe suffering and a high mortality.
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